Medications for Recurrent Calcium Oxalate (CaOx) Stones
HYPERCALCIURIA
• Thiazides: HCT, Indapamide, Chlorthalidone
• Consider after first stone if
- Single kidney
- Large stone burden
± K citrate
HYPOCITRATURIA
• Potassium citrate
• Benefit also outweighs risk in CaPO4 stones
• Also consider if low UPH
HYPERURICOSURIA (with normal UCa)
• Allopurinol
• Mechanism unclear ? Nidus effect
• No data for hypercalciuric patients
NO ABNORMALITIES (or all addressed)
• K citrate ± thiazide
• K citrate preferred first line (lower side-effect profile)
Dr. John Booth @ThePeanutKidney
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