Causes of Anterior Uveitis - Differential Diagnosis Anterior Uveitis - 90% of cases of Uveitis • Inflammation of middle layer of the eye • Anterior-iris +/-ciliary body, Iritis=anterior uveitis • Posterior-choroid • Panuveitis: anterior chamber, vitreous humor, and retina or choroid Unilateral • Inflammatory: HLA-B27 related - isolated or 2ndary to spondylarthritis, Posner-Schlossman Syndrome • Infectious: HSV and toxoplasmosis (common), VZV, syphilis, TB, post-strep, Immunocompromised-CMV • Chronic Inflammatory: Sarcoid, JIA Bilateral: • Inflammatory: Behcet's, SLE, TINU syndrome (w/ renal involvement) • Medication: Rifabutin • Idiopathic: Unilateral/bilateral up to 30% of cases • Mimics: Malignancy - Leukemia/Lymphoma Pearl: Acute onset anterior uveitis in an elderly patient is likely HSV/VZV. In young patient/ consider HIA B27-related syndrome - Dr. Ann Marie Kumfer @AnnKumfer #Anterior #Uveitis #Differential #Diagnosis #Causes #ophthalmology
