Summary of Agents Potentially Contributing to False Positives on Urine Drug Screens (UDS) Marijuana Metabolites • dronabinol, efavirenz, NSAIDs*, hemp foods: tea, oil, proton pump inhibitors Cocaine Metabolites • coca leaf teas, topical anesthetics containing cocaine Opioid Metabolites • dextromethorphan, fluoroquinolones, levofloxacin, ofloxacin, poppy seeds, poppy oil, rifampin, quinine Amphetamines/Methamphetamine (High Rate of False Positives) • amantadine, benzphetamine. dextroamphetamine, doxepin, ephedrine, fluoxetine, isometheptene, isoxsuprine, labetalol, I-methamphetamine (OTC nasal inhaler), methylphenidate, MDMA, phentermine, phenylephrine, phenyl-propanolamine, brompheniramine, bupropion, chlorpromazine, desipramine, promethazine, pseudoephedrine, ranitidine, selegiline, thioridazine, trazodone, trimethobenzamide, trimipramine Benzodiazepines • oxaprozin, sertraline Barbiturates • ibuprofen, naproxen Methadone • chlorpromazine, clomipramine, diphenhydramine, doxylamine, thioridazine, ibuprofen, verapamil, quetiapine Alcohol • mouthwash, short-chain alcohols, OTC cough products (isopropyI alcohol) *NSAlDs resulting in false-positive for marijuana mainly consist of ibuprofen and naproxen and modern tests do not result in false positives; + THC concentrations in hemp products are low enough to prevent positive immunoassay results. #FalsePositives #Urine #DrugScreening #UDS #Testing #Laboratory #diagnosis
