Acute Babesiosis Management Mild/Moderate Disease Severity • Symptoms: Fevers, fatigue, malaise. Headache, nausea. Chills, dyspnea, neck stiffness • Parasite Burden: <4% • Treatment: Azithro 500 mg PO daily+ Atovaquone 750 mg PO BID • Duration: 7-10 days Severe Disease Severity • Symptoms: Same as above. Also ARDS, ARE DIC, shock, splenic rupture/infarcts • Parasite Burden: <4% • Treatment: Azithro 500 mg IV daily + atovaquone 750 mg po BID. Transition to PO azithro after parasitemia diminishes • Duration: Usually 2 weeks, >6 weeks if the patient is immunocompromised - Dr. Kevin Braghirol @KBrag_MD #Babesiosis #Management #treatment #Babesia #microti