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Summary of Timeline of COVID-19 SARS-CoV-2 Infectivity Day 0 - Peak Viral Load and Infectivity Day 5 - Majority of Secondary Infections Occur Prior to This Point Day 10 - Virus Unable To Be Cultured in Mild- Moderate Ilness Beyond This Point Day 15 - <5% Probability of Culturing Virus in Severe-Critical Illness or Immuno-compromised Patients Beyond This Point Day 20 - Longest Duration of Infectious Shedding By Culture Reported To Date Day 90+ - Persistent or Recurrent Positive PCR Possible up To This Point or Beyond (High Ct Values and Not Contagious) Ssummarizes the evidence-to-date on the duration of SARS-CoV-2 Infectivity & when is it Safe to discontinue Isolation: https://academic.oup.com/cid/advanc #Timeline #COVID19 #SARSCoV2 #Infectivity #contagiousness #diagnosis #infection #prevention #isolation #precautions