Shock and Vasoactive Drugs
1) Determine type and etiology of shock
• Distributive: Sepsis, Anaphylaxis, Neurogenic
• Cardiogenic: Acute MI, Acute Heart Failure, Valvular Disease, Mechanical Defect (papillary muscle rupture, VSD, etc.), Ventricular Arrhythmias / CHB
• Hypovolemic: Bleeding, Extreme Dehydration, Severe Burns, Pancreatitis
• Obstructive: Pericardial tamponade, Pulmonary embolism
2) Understand vasoactive drug pharmacology
• Pure Vasoconstrictors: Vasopressin, Phenylephrine
• Ino-Constrictors: Norepinephrine, Epinephrine, Dopamine
• Ino-Dilators: Dobutamine, Isoproterenol, Milrinone
• Pure Vasodilators: Nitroglycerin, Nitroprusside, Nesiritide
3) Treat shock & address underlying etiology
Dr. Hasan Kazmi @hasankazmi01
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