Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Nodular LCH: - Sarcoidosis ... Cystic LCH: - LAM ... ring sign'. - Centrilobular ... #CTChest #Cystic ... Comparison #Table #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Centrilobular emphysema ... histiocytosis (LCH ... #Clinical #Radiology ... #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
LCH: multiple round ... Centrilobular emphysema ... #Clinical #Radiology ... #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
Nodular pattern
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary TB: random nodules
3. Sarcoidosis: nodules with perilymphatic
pneumonitis: ill defined centrilobular ... Hypersensitivity pneumonitis: centrilobular ... #Clinical #Radiology ... #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
HRCT findings in Langerhans cell histiocytosis:
Early stage:
- Small irregular or stellate nodules in centrilobular location.
Late stage
HRCT findings in ... in centrilobular ... #Clinical #Radiology ... #CTChest #LCH # ... Histiocytosis #RadiologyAssistant
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
pneumonitis: ill defined centrilobular ... before the typical cysts ... Clinical #Diagnosis #Radiology ... #Pulmonary #CTChest ... Comparison #Table #RadiologyAssistant
Algorithm for nodular pattern
The algorithm to distinguish perilymphatic, random and centrilobular nodules is the following:
- Look
perilymphatic, random and centrilobular ... #Diagnosis #Radiology ... #Pulmonary #HRCT ... #CTChest #NodularPattern ... Differential #Algorithm #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Nodular pattern( ... before the typical cysts ... #Clinical #Radiology ... #HRCT #CTChest ... Comparison #Table #RadiologyAssistant
On the left another case of Langerhans' cell histiocytosis.
It started as small noduli, which progressed over
started as small noduli ... bizarre shaped cysts ... #Clinical #Radiology ... #CTChest #LCH # ... #RadiologyAssistant
Cystic versus Reticular
It can be difficult to determine whether we are dealing with a reticular pattern
LCH is called a ... of such cases a HRCT ... #Clinical #Radiology ... #CXR #CTChest # ... #RadiologyAssistant