Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Insulin Dosing Basics - Initiating Insulin for T2DM and Converting Insulin Products 

Insulin dosing can be
Insulin Dosing Basics ... doses if patients ... , decrease the dose ... , decrease the dose ... #Conversion #Initiating
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
on the highest dose ... only use lower doses ... at the lowest dose ... make sure the dose ... #Pharmacology #
Insulin Degludec (Tresiba) vs Insulin Glargine (Lantus, Basaglar, or Toujeo)

Insulin degludec (Tresiba) is an ultra-long acting
never needs to be dosed ... do require BID dosing ... glargine if it does ... Glargine #Comparison #Pharmacology ... #DEVOTE #Diabetes
Insulin Calculations for Type 1 Diabetes 

Insulin-to-Carb Ratio (ICR) 500/TDD = #g of carbs covered by
calculations used in dosing ... dose, but will ... normal mealtime dose ... #DM1 #Pharmacology ... #Endocrinology
Diabetes Morning Hyperglycemia - Dawn Phenomenon vs Somogyi Effect 

When patients FBG's are elevated each morning
growth hormones and insulin ... patient actually does ... their evening insulin ... dose which actually ... Diagnosis #Management #Endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 β€’ Suppresses gluconeogenesis by the liver
 β€’ Increases insulin-mediated glucose utilization
Metformin Pharmacology ... β€’ Increases insulin-mediated ... oral agent β€’ Does ... #Summary #DM2 #diabetes ... #endocrinology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
GLP-1 Agonist Dosing ... mg maintenance dose ... smaller starting dose ... the maintenance dose ... the maintenance dose
IDSA Recommendations for Treating Cytomegalovirus Infections in HIV-AIDS
Preventing CMV Disease:
 β€’ CMV end-organ disease is best
IDSA Recommendations ... best prevented by using ... injection) for 1–4 doses ... Treatment #management #opportunistic ... infections #HIVAIDS #pharmacology
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS
Treating LTBI (to prevent TB disease)
Indications:
IDSA Recommendations ... months or β€’ RFB (dose ... Guidelines for dosing ... Treatment #management #opportunistic ... infections #HIVAIDS #pharmacology