Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Amphoterecin B, Abelcet ... , Ambisome - Antibiotics ... Class Overview ... #Pharmacology #Antibiotics ... #Review #Overview
ANTIBIOTICS WITH ANAEROBE COVERAGE - Antibiotics Class Overview
 1. Metronidazole (Flagyl)(PO and IV)
 2. Clindamycin –
ANTIBIOTICS WITH ... - Antibiotics Class ... Overview 1. ... #Pharmacology #Antibiotics ... #Review #Overview
Carbapenems - Antibiotics Class Overview

Imipenem/Cilastin, Meropenem, Ertapenem, Doripenem 

Spectrum: Broadest spectrum antibiotics, cover Gram positive, Gram
Carbapenems - Antibiotics ... Broadest spectrum antibiotics ... producers), also anaerobes ... #Pharmacology ... #Antibiotics #Review
Tigecycline (IV) - Antibiotics Class Overview

Mechanism: Glycylcycline class - structurally related to Tetracyclines (bacteriostatic).  Only
Tigecycline (IV) - Antibiotics ... Class Overview ... Gram negatives, anaerobes ... #Pharmacology #Antibiotics ... #Review #Overview
Anti-C. Difficile - Antibiotics Class Overview
 1. Metronidazole – (see anti-anaerobe section above for more details).
Difficile - Antibiotics ... Class Overview ... Metronidazole – (see anti-anaerobe ... Fidaxomicin (PO) #Pharmacology ... #Antibiotics #Review
Aminoglycosides  - Antibiotics Class Overview

Gentamicin, Tobramycin, Amikacin, Streptomycin -30S inhibitor (all IV)
Spectrum: Extremely efficacious vs.
Aminoglycosides - Antibiotics ... Class Overview ... for synergy) or anaerobes ... #Pharmacology #Antibiotics ... #Review #Overview
Clindamycin - Antibiotics Class Overview
-50 S inhibitor (PO and IV)
Spectrum: Excellent activity vs. Anaerobes and Gram
Clindamycin - Antibiotics ... Class Overview ... Anaerobes and Gram ... pyrimethamine) #Pharmacology ... #Antibiotics #Review
Sulfonamides - Antibiotics Class Overview

BACTRIM/SEPTRA (TMP/SMX) - inhibit sequential steps in Folate synthesis --> bacteriostatic

Spectrum: Wide
Sulfonamides - Antibiotics ... Class Overview ... BACTRIM/SEPTRA ... #Pharmacology #Antibiotics ... #Review #Overview
Monobactam - Aztreonam - Antibiotics Class Overview

Spectrum: only has activity vs. aerobic gram negatives, no gram
- Aztreonam - Antibiotics ... Class Overview ... gram positive or anaerobes ... combination with other antibiotics ... #Pharmacology #Antibiotics
Chloramphenicol - Antibiotics Class Overview

– 50S ribosomal inhibitor.   IV or PO (but PO form
Chloramphenicol - Antibiotics ... Class Overview ... NOT Pseudomonas; Anaerobes ... Chloramphenicol +/- Bactrim ... #Pharmacology #Antibiotics