Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... applications in anaphylaxis ... beta-blocker overdose #Toxicology ... #Pharmacology # ... Pathophysiology
Ethylene Glycol Toxicity

#Pathophysiology #Toxicology #EthyleneGlycol #Metabolism #Fomepizole
Ethylene Glycol Toxicity ... #Pathophysiology ... #Toxicology #EthyleneGlycol
Cyanide Toxicity 
Treatment:
1) Hydroxocobalamin + Cyanide = Cyanocobalamin (nontoxic) 
   or 
2) Amyl nitrite
Cyanide Toxicity ... #Cyanide #Toxicity ... #Toxicology #Pathophysiology
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #ILE #Therapy #Toxicology ... #Management #Pharmacology
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... Symptoms of GHB toxicity ... Hydroxybutyrate #GHB #Toxicology ... #Toxicity #Diagnosis ... #Management #Pharmacology
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... Carbamazepine #Toxicity ... #Toxicology #Diagnosis ... SideEffects #Adverse #Pharmacology
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Valproic Acid Toxicity ... Antibiotics #Antidotes #Toxicology ... #Pharmacology
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
factors affecting toxicity ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology
Nitrofurantoin Toxicology
Serious Adverse Effects:
Hemolysis in patients with G6PD-deficiency
Peripheral neuropathy
Hepatitis
Pulmonary toxicity
Nephritis

By Dr. Kathryn Watson @Kat_Watson

#Nitrofurantoin #Macrobid #Toxicity
Nitrofurantoin Toxicology ... Hepatitis Pulmonary toxicity ... Nitrofurantoin #Macrobid #Toxicity ... #Toxicology #Pharmacology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... LacticAcidosis #Toxicity ... #Toxicology #Diagnosis