Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Aplastic Anemia ... Acquired Aplastic ... BoneMarrow #Failure #Aplastic ... #anemia #diagnosis ... #Hematology
Aplastic Anemia Summary

 β€’ Definition
 β€’ Pathophysiology
 β€’ DDx: AA vs Hypocellular MDS
 β€’ Expectation
 β€’
Aplastic Anemia ... @ZhuoerXie #Aplastic ... #Anemia #diagnosis ... #oncology #hematololgy
Lobar consolidation
The most common presentation of consolidation is lobar or segmental.
The most common diagnosis is lobar
The most common diagnosis ... the differential diagnosis ... #Diagnosis #Radiology ... #Pulmonary #CXR ... #Differential #RadiologyAssistant
Aplastic Anemia - Illness Script
Signs and symptoms:
 β€’ Recurrent infections from neutropenia
 β€’ Mucosal bleeding from
Aplastic Anemia ... Diagnosis: β€’ Pancytopenia ... Medicine @SCVMCMed #Aplastic ... #Anemia #diagnosis ... management #treatment #hematology
Here are the most common examples of these four patterns on a chest x-ray (click image
Consolidation - Lobar ... mass - Solitary Pulmonary ... Masses Atelectasis #Diagnosis ... Clinical #Radiology #CXR ... Consolidation #Patterns #RadiologyAssistant
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... dys- (abnormal) -plastic ... 10,000 new cases diagnosed ... cytopenias (usually anemia ... Management #treatment #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Index < 2: β€’ Anemia ... marrow failure: Aplastic ... anemia, Marrow ... Production #Index #hematology ... #diagnosis #calculation
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... FISH β€’ Acquired Aplastic ... Anemia β€’ Hypoplastic ... #Differential #Diagnosis ... #Algorithm #Hematology
Red Blood Cell (RBC) Morphology Atlas
 β€’ Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Sideroblastic anemia ... PD deficiency, Pulmonary ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential Diagnosis ... FISH β€’ Acquired Aplastic ... Anemia β€’ Hypoplastic ... #Differential #Diagnosis ... #Algorithm #Hematology