Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
- This table summarizes ... toxidrome β€’ Sympathomimetic ... #Syndromes #Comparison ... #Table #Diagnosis ... #Toxicology #Hyperthermia
Signs and Symptoms of Toxidromes

Sympathomimetic / GABAergic withdrawal 
Cholinergic 
Anticholinergic 
Opioid withdrawal 
Neuroleptic malignant syndrome 
Serotonin
Toxidromes Sympathomimetic ... #Toxidromes #Comparison ... #Table #Anticholinergics ... #Opioids #Sympathomimetics ... #Diagnosis #Toxicology
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
caused by specific medications ... barbituates, β€œZ-drugs ... antihistamines #Diagnosis ... #Toxicology #Toxidromes ... #Comparison #Table
Toxidromes Summary Table
Heart Rate - Respiratory Rate - Blood Pressure - Mental Status - Skin -
Toxidromes Summary Table ... Sedative/hypnotic β€’ Sympathomimetic ... #Toxidromes #comparison ... #table #toxicology ... #diagnosis
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
Cholinergic, Opioid, Sympathomimetic ... #Diagnosis #Toxicology ... #Toxidromes #Comparison ... #Table #Anticholinergics ... #Opioids #Sympathomimetics
The RIGID patient: tetanus mimics
 - Serotonin Syndrome
 - Neuroleptic Malignant Sx
 - Malignant Hyperthermia
 -
- Malignant Hyperthermia ... - Drug-induced ... tetanus #mimics #comparison ... #table #rigidity ... #differential #diagnosis
Fever vs Hyperthermia
Fever:
 β€’ Regulated in the hypothalamic thermoregulatory center
 β€’ "Set point" raised by prostaglandin
production β€’ Treatment ... fatal β€’ Causes: Drugs ... Serotonin syndrome β€’ Treatment ... #comparison #diagnosis ... #management #treatment
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 β€’ Sympathomimetic -
Hyperthermic Toxidromes ... β€’ Sympathomimetic ... #Toxidromes #comparison ... #table #diagnosis ... #differential #toxicology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or β‰₯ 39 C this is a
Peri-operative Hyperthermia ... Treatment depends ... anaphylaxis (β†’ 3-1) Drug ... antihistamines) β€’ Sympathomimetic ... Anesthesia #Checklist #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 β€’ Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms β€’ Treatment ... life-threatening β€’ Treatment ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management