Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Differential diagnosis of Langerhans cell histiocytosis.
Nodular LCH:
- Sarcoidosis: perilymphatic distribution.
- Metastases: random distribution.
Cystic LCH:
- LAM: round
Langerhans cell histiocytosis ... central dot. - LIP #Clinical ... #Diagnosis #Radiology ... #Comparison #Table ... #RadiologyAssistant
On the left three different patients with lung cysts.
From left to right: Lymphangiomyomatosis, LIP and Langerhans
patients with lung cysts ... #Clinical #Diagnosis ... #Radiology #CTChest ... #Cystic #Comparison ... #RadiologyAssistant
Low Attenuation pattern (2) 
1. Centrilobular emphysema: low attenuation areas without walls. Notice the centrilobular artery
Langerhans cell histiocytosis ... (LAM): regular cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Nodular pattern(2)
1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy.
2. TB: Tree-in-bud appearance in a patient
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
Low Attenuation pattern 
1. Lymphangiomyomatosis (LAM): uniform cysts in woman of child-bearing age; no history of
(LAM): uniform cysts ... bizarre shaped cysts ... #Clinical #Radiology ... Pattern #Comparison #Table ... #RadiologyAssistant
On the left another case of Langerhans' cell histiocytosis.
It started as small noduli, which progressed over
Langerhans' cell histiocytosis ... bizarre shaped cysts ... #Clinical #Radiology ... LangerhansCellHistiocytosis #Histiocytosis ... #Cystic #RadiologyAssistant
HRCT findings in Langerhans cell histiocytosis:
Early stage:
- Small irregular or stellate nodules in centrilobular location.
Late stage
Langerhans cell histiocytosis ... airspaces Cysts ... There are no cysts ... #Clinical #Radiology ... #RadiologyAssistant
High Attenuation pattern 
1. Chronic eosinophilic pneumonia with peripheral areas of ground glass opacity.
2. Sarcoid end-stage
Chronic eosinophilic pneumonia ... consolidation #Clinical ... #Radiology #HRCT ... Pattern #Comparison #Table ... #RadiologyAssistant
On the left some diseases with a nodular pattern.
1. Hypersensitivity pneumonitis: ill defined centrilobular nodules.
2. Miliary
Langerhans cell histiocytosis ... before the typical cysts ... #Clinical #Diagnosis ... Differential #Comparison #Table ... #RadiologyAssistant
Differential diagnosis on HRCT
Most of our knowledge about imaging findings in interstitial lung disease comes from
low attenuation (table ... The cystic pattern ... Langerhans cell histiocytosis ... #Diagnosis #Radiology ... #Differential #RadiologyAssistant