Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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diagnosis management betadglucan galactomannan biomarkers bloodstream catheter chalazion crbsi ctchest falsepositives granuloma hordeolum ia infection infectiousdiseases invasive laboratory majocchis microscopy
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
eg. allogeneic HSCT ... HIV/AIDS, CGD) Clinical ... this morphology Treatment ... Diagnosis #Management #treatment ... #fungal #infectiousdiseases
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... cut-offs defined in clinical ... surfaces - Infections ... and allogeneic HSCT ... Galactomannan #diagnosis #comparison
Nodular pattern(2) 1. Sarcoidosis: nodules with perilymphatic distribution, along fissures, adenopathy. 2. TB: Tree-in-bud appearance in a patient
bronchiolitis in infection ... #Clinical #Radiology ... #HRCT #CTChest ... Nodular #Pattern #Comparison ... #Table #RadiologyAssistant
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
component of many fungi ... cut-offs defined in clinical ... surfaces, Albumin, Infections ... >90% (In most clinical ... 100d following HCT
Hordeolum vs Chalazion Hordeolum (Stye): • Location: Most commonly found at or near an eyelash follicle •
Cause: Bacterial infection ... , swelling • Treatment ... eyedrops, surgery #Clinical ... Stye #Chalazion #Comparison ... #Table
Suspected catheter-related bloodstream infection - Management Algorithm • Temperature 37.8 C • Rigors
- Management Algorithm ... Hemodynamically stable ... pathogens (S. aureus, fungal ... after treatment ... #Management #Algorithm
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
Treatment: Itraconazole ... Non-dermatophytes: Aspergillus ... Majocchi granuloma Treatment ... Fungal infection ... recommended Mayo Clinic
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