Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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diagnosis rheumatology ana antibodies antinuclear differential management nephrology sclerosis signs ssc symptoms testing workup
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(SSc): • Limited ... distal to elbows/wrists ... arterial HTN) • Renal ... : scleroderma renal ... crisis (SRC)
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Juvenile Idiopathic Arthritis ... (SSc) • Nucleolar ... sclerosis/scleroderma ... Antibodies #ANA #patterns
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
: The ANA patterns ... Juvenile Idiopathic Arthritis ... (SSc) • Nucleolar ... ), Rheumatoid Arthritis ... Juvenile Idiopathic Arthritis
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Scleroderma Renal ... Crisis (SRC) ... Renal Crisis: ... onion-skinning" of arteries ... #Scleroderma #Renal
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