The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
: Gastrointestinal ... Vasculitis -> Acute ... #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Systemic Lupus Erythematosus ... #Systemic #Lupus ... Musculoskeletal #Complications ... pathophysiology #signs #symptoms ... #diagnosis
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... minor trauma #AnkylosingSpondylitis ... pathophysiology #diagnosis ... #signs #symptoms
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Acute onset of skin ... in the acute phase ... / Complications ... pathophysiology #immunology #diagnosis
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Subacute cutaneous lupus ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... severe Signs/Symptoms ... Balance Problems #Acute ... pathophysiology #symptoms ... #signs #diagnosis
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Clinical Findings and Complications ... are more acute ... The less acute behavioral ... myalgias) - Gastrointestinal ... Pathophysiology #Diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... , Carditis #Acute ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... /Complications: ... TendonRupture #diagnosis ... #signs #symptoms