The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis symptoms psychiatry behavioraldisorder mooddisorders msk vasculitis acute adhd affectivedisorder arteritis aspd attentiondeficithyperactivedisorder benign bipolar bph cd cecs chronicexertional compartmentsyndrome
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Major Depressive ... included in DSM 5 criteria ... MajorDepressiveDisorder #Depression ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
inflammatory cytokine expression ... yrs old; F>M Signs ... Temporal #Arteritis #Pathophysiology ... #Diagnosis #Signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
pathway -> Incr gene expression ... activates lipolysis Signs ... endocrinology #pathophysiology
Glucocorticoid-Induced Osteoporosis: Pathogenesis and Clinical Findings • Negative feedback on hypothalamus/pituitary, Decreasing ACTH -> Decr Sex
Upregulate gene expression ... #Osteoporosis #pathophysiology ... #signs #symptoms
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings Work & lnterpersonal: • Home Life Troubles - Conflict
Antisocial Personality ... disorder #ASPD #Antisocial ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Xeropthalmia: Pathogenesis and Ocular Manifestations Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
& Decr surface expression ... #Xeropthalmia #pathophysiology ... ophthalmology #diagnosis #signs
Schizophrenia: Pathogenesis and Symptoms Increased dopaminergic transmission in mesolimbic projection -> Dopaminergic neurons here project into the limbic
Diminished emotional expression ... Schizophrenia #pathophysiology ... diagnosis #symptoms #signs
Bipolar Disorder: Pathogenesis and Clinical Findings • Disruption of emotional homeostasis • Oscillation between mood states
maintain this state Depressive ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
present -> Anxiety, depression ... #Dysfunction #Pathophysiology ... #Urology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
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