The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Stevens-Johnson Syndrome ... Dermatitis (ie. reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reactionType ... reactionType ... reactionType ... #Types #Classification ... #Diagnosis #Definitions
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... causes development ... Allergic reaction ... Stevens-Johnson Syndrome ... ivy) #TypeIV #Type4
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... reaction -> Benign ... Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry