The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Hypersensitivity: Summary Type ... conjunctivitis Type ... Stevens-Johnson Syndrome ... #Classification ... #Diagnosis #Definitions
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... SSRI Withdrawal Syndrome ... Dizziness - Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Open Fractures: Mechanisms, Clinical Features and Complications
Gustilo-Anderson Classification:
 • Type I
   - Wound <
Gustilo-Anderson Classification ... : • Type I ... comminution • Type ... GustiloAnderson #Classification ... Open #Fractures #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vomiting Serotonin Syndrome ... gain Incr NE: Nausea ... #SideEffects #Psychiatry ... #Diagnosis #Signs
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... exposure to allergen causes ... Stevens-Johnson Syndrome ... ivy) #TypeIV #Type4
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... Systemic effect -> Nausea ... Pathophysiology #Psychiatry
Schizophrenia: Pathogenesis and Symptoms
Increased dopaminergic transmission in mesolimbic projection
-> Dopaminergic neurons here project into the limbic
is thought to cause ... is thought to cause ... pathophysiology #diagnosis ... symptoms #signs #psychiatry
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
(Type, Range, Appropriate ... Thought Content - Types ... , the symptoms caused ... MentalStatusExam #MSE #psychiatry ... #diagnosis #evaluation
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications
 • Anterior Posterior Compression (APC) -
Classification of ... - LC Grade 3 - Type ... PelvicRing #Fractures #Classification ... Orthopedics #MSK #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... Causes: • Large ... #CaudaEquina #Syndrome ... pathophysiology #diagnosis