The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry ... #Diagnosis #Signs ... #Symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
auto-reactive B and CD ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... MoodDisorders #Diagnosis ... #Pathophysiology ... #Signs #Symptoms
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder (CD ... >18 years old, criteria ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... signs #psychiatry #criteria
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
findings - For diagnosis ... to 25 for new diagnosis ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... signs #psychiatry #criteria
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
Extrapyramidal Symptoms ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology # ... diagnosis #psychiatry
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Injury #Syndromes #diagnosis ... #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Varicocele: Pathogenesis and clinical findings
Primary:
 - Anatomically: the left spermatic vein drains into the left renal
#Varicocele #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms ... #Urology #Diagnosis