The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Bipolar Disorder: Pathogenesis and Clinical Findings
 • Disruption of emotional homeostasis
 • Oscillation between mood states
Bipolar Disorder ... - Incr guilt, anxiety ... behaviours #Bipolar ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Pathogenesis of Anxiety Disorders

Anxiety Disorders: A maladaptive emotional state causing fear,
worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... acid (GABA) #Anxiety ... #Disorders #Pathophysiology ... #diagnosis #psychiatry
Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
seizure, relapse of bipolar ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Treating DKA: 1) ... #pathophysiology ... #endocrinology
Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
, seizure, and anxiety ... AlcoholUseDisorder #EtOH #Pathophysiology ... Signs #Symptoms #Psychiatry
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
partum onset) - Anxiety ... MoodDisorders #Diagnosis #Pathophysiology ... Signs #Symptoms #Psychiatry
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis
 • Bipolar Disorder -> Combination of individual, genetic,
Pathogenesis • Bipolar ... Differential #Diagnosis #Pathophysiology ... #Psychiatry
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
carrying anti-anxiety ... Anticipatory Anxiety ... PanicDisorder #Anxiety ... BehavioralDisorder #Pathophysiology ... symptoms #signs #psychiatry
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
erection present -> Anxiety ... and rigidity Endocrinologic ... #Dysfunction #Pathophysiology