The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diabetes diagnosis excess feedbackloop overproduction pituitary signs
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... Hormone (GH) Growth ... lipolysis Signs/Symptoms ... metabolic abn #GrowthHormone ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... fraction • HTN #GrowthHormone ... diagnosis #signs #symptoms ... #endocrinology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... Signs/Symptoms/Complications ... confusion coma #DiabeticKetoacidosis ... #endocrinology
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