The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... Executive planning dysfunction ... AlzheimersDisease #Dementia #pathophysiology ... geriatrics #diagnosis #signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vomiting Serotonin Syndrome ... Vertigo, Sexual Dysfunction ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... Psychiatry #Diagnosis #Signs
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... #Pathophysiology ... #Urology #Diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... bladder/bowel dysfunction ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
Signs/Symptoms/Complications ... confusion coma #DiabeticKetoacidosis ... #DKA #pathophysiology ... #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Carpal Tunnel Syndrome ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Signs / Symptoms ... • Hypothalamic dysfunction ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
Polycystic Ovarian Syndrome ... MenstrualCycle #OvarianCycle ... #pathophysiology ... FollicularPhase #endocrinology