The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms chondrocalcinosis pseudogout 21ohd acute centralretinalartery closedangle crao endocin excess genetics gh glaucoma gravesdisease growthhormone hyperthyroidism keratoconus occlusion overproduction
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... a scrotum #21HydroxylaseDeficiency ... #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... the etiology Signs ... GravesDisease #pathophysiology ... #endocin #endocrinology ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
rare, gestational diseases ... Signs/Symptoms: ... Hyperthyroidism #endocrinology ... #pathophysiology
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... Chondrocalcinosis #Pseudogout #CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... Cardiovascular disease ... Overproduction #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
rubbing • Atopic diseases ... > Keratoconus Signs ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
Pyrophosphate Dihydrate (CPPD ... ) Deposition Disease ... - Acute CPPD ... #Disease #Signs ... #Symptoms #Pathophysiology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• The disease ... damage & blindness Signs ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
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