The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology c5c9deficiency complement inflammatory xlinked
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... Recruitment • Humoral ... #Inflammatory #Cascade ... #Inflammation # ... pathophysiology #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
X-Linked Agammaglobulinemia ... deficiency in adaptive humoral ... common antigens #Agammaglobulinemia ... pathophysiology #immunology
C5-C9 Deficiency - Pathogenesis and Clinical Findings Note: • Risk of invasive meningococcal disease is 1000-10000x higher
-> Complement cascade ... • Inflammation ... pathophysiology #immunology
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