The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
dead tissue • Complement ... destruction), promote inflammation ... activation of complement ... Inflammatory #Cascade #Inflammation ... pathophysiology #immunology
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
is rare Normal complement ... response: The complement ... activation -> Complement ... • Inflammation ... pathophysiology #immunology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
Benign Prostatic ... Hyperplasia: Pathogenesis ... cell nuclei -> Hyperplasia ... Decreased Prostatic inflammation ... #BPH #Benign
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... Hyperplasia: Pathogenesis ... FGF-related proteins) Inflammation ... stones #BPH #Benign ... #Prostatic #Hyperplasia