The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... dead tissue • Complement ... activation of complement ... #Cascade #Inflammation ... pathophysiology #immunology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings

Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Mixed Urinary Incontinence ... Urgency Urinary Incontinence ... (neurogenic), inflammation ... Incr PVR if a complication ... Pathophysiology #Signs #Symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
endoscopy (Not Inflammatory ... Bladder and bowel incontinence ... AnkylosingSpondylitis #Extraarticular ... Manifestations #Complications ... diagnosis #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
cytokines -> localized inflammatory ... scaling that extend inflammation ... -> Incr local inflammation ... diagnosis #signs #symptoms ... #complications
Psoriatic Arthritis: Complications

 • Ocular - Inflammation of middle layer of the eye (the uvea, which
Psoriatic Arthritis: Complications ... • Ocular - Inflammation ... Valvular disease - Inflammatory ... diagnosis #signs #symptoms ... #Complications
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... Urgency, nocturia, incontinence ... Urology #Signs #Symptoms