The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis adhesivecapsulitis allergy cascade comparison degenerative frozenshoulder hypersensitivityreaction jointdisease jointpain signs stages staging symptoms type1 typei versus
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis: Pathogenesis ... Anaphylaxis is ... production of inflammatory ... Recruitment of inflammatory ... pathophysiology #immunology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... destruction), promote inflammation ... cell activity #Inflammatory ... #Cascade #Inflammation ... pathophysiology #immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
release the pro-inflammatory ... secretion • Inflammatory ... conjunctivitis • Anaphylaxis ... HypersensitivityReaction #Allergy #Immunology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Distinguishing between Inflammatory ... joint disease Inflammatory ... Swollen Joints • Inflammation ... mild synovial inflammation ... Comparison #Versus #MSK
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... stop, but post-inflammatory ... stages #staging #msk
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