The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis symptoms adhesivecapsulitis benign bph centralretinalartery comparison crao degenerative frozenshoulder hyperplasia jointdisease jointpain mastoiditis occlusion ophthalmology otology prostate prostatic
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... T-Cell activation takes ... cells or CTLs -> Inflammation ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... release the pro-inflammatory ... secretion • Inflammatory ... #TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... diagnosis #symptoms #signs ... #msk
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
Otitis Media -> Stage ... mucosa leads to inflammation ... are connected) Stage ... : Extension of inflammatory ... pathophysiology #signs
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
joint disease Inflammatory ... Lots of fluid, takes ... Swollen Joints • Inflammation ... mild synovial inflammation ... Comparison #Versus #MSK
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
clinical findings • Inflammatory ... hypercoagulable state ... Hypercoagulable state ... viscosity and inflammation ... ophthalmology #diagnosis #signs
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... UTIs & bladder stones ... Pathophysiology #Urology #Signs
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