The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis adhesivecapsulitis anaphylaxis cascade comparison degenerative frozenshoulder jointdisease jointpain signs stages staging symptoms type2 type3 type4 typei typeiii typeiv versus
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... cells or CTLs -> Inflammation ... #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
release the pro-inflammatory ... secretion • Inflammatory ... #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Inflammatory Cascade: Pathogenesis and Clinical Findings Continued Innate Immunity • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Inflammatory Cascade ... destruction), promote inflammation ... #Cascade #Inflammation ... #pathophysiology ... #immunology
Anaphylaxis: Pathogenesis Anaphylaxis is a Type 1 hypersensitivity reaction While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis is a Type ... production of inflammatory ... Recruitment of inflammatory ... #Anaphylaxis #pathophysiology ... #immunology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
joint disease Inflammatory ... Swollen Joints • Inflammation ... mild synovial inflammation ... Comparison #Versus #MSK ... JointPain #Diagnosis #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... FrozenShoulder #pathophysiology ... stages #staging #msk
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