The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology comparison diagnosis jointdisease jointpain type1 type4 typei typeiv versus
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... Allergic reaction ... cells or CTLs -> Inflammation ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... release the pro-inflammatory ... secretion • Inflammatory ... #TypeI #Type1 #HypersensitivityReaction ... #Allergy #Immunology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
and Degenerative ... Swollen Joints • Inflammation ... mild synovial inflammation ... #Degenerative # ... Comparison #Versus #MSK
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