The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology comparison diagnosis jointdisease jointpain type1 type2 type3 type4 typeiii typeiv versus
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... cells or CTLs -> Inflammation ... Poison ivy) #TypeIV ... #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... release the pro-inflammatory ... secretion • Inflammatory ... #Type1 #HypersensitivityReaction ... #Allergy #Immunology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... #HypersensitivityReaction ... #Allergy #Immunology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
and Degenerative ... Swollen Joints • Inflammation ... mild synovial inflammation ... #Degenerative # ... Comparison #Versus #MSK
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