The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
T-Cell activation takes ... cells or CTLs -> Inflammation ... TypeIV #Type4 #HypersensitivityReaction ... #Allergy #Immunology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
shoulder joint inflammation ... as post-inflammatory ... shoulder joint inflammation ... stop, but post-inflammatory ... #staging #msk
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Lots of fluid, takes ... Swollen Joints • Inflammation ... mild synovial inflammation ... #Degenerative #Comparison ... #Versus #MSK #JointDisease
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
alterations (result of aging ... FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... activation of inflammatory ... UTIs & bladder stones
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
this process) Inflammatory ... of hematoma -> Inflammatory ... NSAlDs - Block the inflammatory ... #Orthopedics #msk ... #Staging #pathophysiology