The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis growthhormone differential feedbackloop femur menstrualcycle orthopedics ovariancycle overproduction pituitary signs subtrochanteric symptoms uterinecycle
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... • Other rare causes ... Acne • Coarse features ... signs #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... /Symptoms: • GH ... deficiency: - Short ... excess: - ... #FeedbackLoop #endocrinology
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... in elderly Causes ... Major trauma -> An excess ... #msk #orthopedics ... #differential #causes
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
days long) • Starts ... , progesterone causes ... pathophysiology #comparison ... #endocrinology
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