The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology diagnosis psychiatry 21hydroxylasedeficiency 21ohd bulimianervosa caudaequina cecs chronic chronicexertional compartmentsyndrome diabetes diabeticketoacidosis dka erythematosus genetics glftap hypertensive lupus macroadenoma
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
A good mnemonic ... Signs / Symptoms ... / Complications ... #SideEffects #endocrinology ... #mnemonic #GLFTAP
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... #signs
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... -> Cotton-wool Spots ... -> Elschnig's Spots ... ophthalmology #diagnosis #signs ... #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
out of cells may cause ... anion gap until it closes ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... pathophysiology #endocrinology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
activity that causes ... • Diagnostic criteria ... pathophysiology #diagnosis #signs ... #symptoms #msk
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... and Symptoms Associated ... related to complications ... • Sores, scars ... , calluses on knuckles
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... pathophysiology #diagnosis #signs ... #symptoms #complications
Obsessive-Compulsive Personality Disorder (OCPD): Pathogenesis and Clinical Findings • Miserly - Lack of generosity when it
themselves; hoard in case ... value OCPD Mnemonic ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms ... #Mnemonic #SCRIMPER
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