The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs peds genetics 21hydroxylasedeficiency 21ohd alzheimersdisease bulimianervosa cecs childhood chronicexertional compartmentsyndrome complications constipation dementia endocrinology hypertensive immunization ophthalmology
Childhood Immunization Schedule: Why we immunize • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
Tetanus Toxin -> Spores ... hemorrhagic rash; symptoms ... lymph -> Koplik's spots ... non-specific viral symptoms ... Immunization #peds #pediatrics
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
Chronic Hypertensive ... • Acute and chronic ... -> Cotton-wool Spots ... -> Elschnig's Spots ... diagnosis #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer's (99% of cases ... Alzheimer's (1% of cases ... chromosome 21) Signs / Symptoms ... pathophysiology #geriatrics ... diagnosis #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Syndrome Signs/Symptoms ... fractures • Short ... pathophysiology #peds #pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... endocrinology #peds #pediatrics
Pathogenesis of Select Causes of Constipation in Adults and in Elderly • Mechanical (ex. Bowel Obstruction,
Pathogenesis of Select Causes ... Digestion and colonic ... deposits into colonic ... contractions -> Incr Colonic ... pathophysiology #geriatrics
Chronic Exertional Compartment Syndrome (CECS) • Diagnosis Of CECS requires patient to undergo the same exertional
Chronic Exertional ... activity that causes ... diagnosis #signs #symptoms ... #msk
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Nervosa: Signs and Symptoms ... gum disease from chronic ... indication of chronic ... Russell's Sign • Sores ... , scars, calluses
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