The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Biomechanical Factors • Contact ... > Keratoconus Signs ... / Symptoms / Complications ... • Rizutti's Sign ... pathophysiology #ophthalmology
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
Hypertension Stage ... -> AV nicking Stage ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Mental Status Exam (MSE)
Note: The MSE is a "snapshot" of a patient at a specific time.
You
Mental Status Exam ... clothing, appears stated ... activity, eye contact ... , avoiding eye contact ... #psychiatry #diagnosis
Avoidant Personality Disorder (AVPD): Pathogenesis and Clinical Findings
 • Restraint - Shows excessive restraint in intimate
interpersonal contact ... interpersonal contact ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
damage & blindness Signs ... / Symptoms / Complications ... scotomas of various shapes ... pathophysiology #ophthalmology
Antisocial Personality Disorder (ASPD): Pathogenesis and Clinical Findings
Work & lnterpersonal:
 • Home Life Troubles - Conflict
and evidence of conduct ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings
 • Arrogant, Haughty Behaviors or Attitude - Often display
positive self-states ... PersonalityDisorder #Diagnosis #Psychiatry ... #Criteria #Signs
Conduct Disorder (CD): Pathogenesis and clinical findings
 - Must have >3 symptoms present in the past
Conduct Disorder ... >18 years old, criteria ... lengthy period • Stays ... diagnosis #symptoms #signs ... #psychiatry #criteria
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: Complications ... bone formation MSK ... Nephrolithiasis (Kidney Stones ... pathophysiology #diagnosis #signs ... #symptoms #complications
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
combination of mental status ... Altered Mental Status ... Serotonin Toxicity Criteria ... Pathophysiology #Psychiatry ... #Diagnosis #Signs