The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... not always) the anterior ... Signs / Symptoms ... #SideEffects #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis
Estrogen, when released:
 • Negatively feeds back on the hypothalamus and
hypothalamus and anterior ... pituitary to Decreased ... hypothalamus and anterior ... pituitary to Increased ... HypothalamicPituitary #endocrinology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
Anterior Shoulder ... • Humeral head anterior ... bone -> Pain #Anterior ... Diagnosis #signs #symptoms ... #msk #orthopedics
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
production by pituitary ... feeding back on anterior ... pituitary which ... effect on the anterior ... FollicularPhase #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
acetabular wall • Anterior ... femoral head onto anterior ... lateral hip Signs/Symptoms ... pathophysiology #signs #symptoms ... #orthopedics
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology ... pathophysiology #pituitary
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
feedback on the anterior ... pituitary (switch ... pathophysiology #Ovulation #endocrinology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
inflammation of the interior ... periorbital tissue (anterior ... pathophysiology #ophthalmology ... diagnosis #signs #symptoms
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings • Anterior ... Cord Syndrome -> Anterior ... pathophysiology #signs #symptoms ... #msk #orthopedics