The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis symptoms pediatrics endocrinology retinopathy genetics 21hydroxylasedeficiency 21ohd acute bulimianervosa chronic closedangle diabetic diabeticketoacidosis dka glaucoma glftap hypertensive incontinence keratoconus
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Obesity -> Type 2 diabetes ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... #Retinopathy #Diabetes ... #ophthalmology ... #diagnosis #complications ... #pathophysiology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs ... / Symptoms / Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings Predisposing Factors: - Immunocompromised, Diabetes, - Elderly, Female
Immunocompromised, Diabetes ... lower tract: As a complication ... UrinaryTractInfection #UUTI #Pathophysiology ... #Signs #Symptoms
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... endocrinology #diabetes
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
> Keratoconus Signs ... / Symptoms / Complications ... • Rizutti's Sign ... #Keratoconus #pathophysiology ... #ophthalmology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... #OtitisMedia #pathophysiology ... diagnosis #symptoms #signs ... #peds #pediatrics
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms ... / Complications ... Hyperprolactinemia • Diabetes ... mnemonic #GLFTAP #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... #21HydroxylaseDeficiency #21OHD #pathophysiology ... endocrinology #peds
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
cystitis, UTI), diabetes ... Incr PVR if a complication ... Incontinence #Mixed #Pathophysiology ... #Signs #Symptoms
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