The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... sickness #TypeIII #Type3 ... #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings
Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... Poison ivy) #TypeIV ... #Type4 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction ... #Allergy #Immunology ... #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... SSRIs #Serotonin #Inhibitors ... #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Anaphylaxis is a Type ... #Anaphylaxis #pathophysiology ... #immunology
Benign Prostatic Hyperplasia: Pathogenesis and Medications
Aging
 -> Increased Testosterone -> Testosterone metabolized into DHT by type
metabolized into DHT by type ... outflow - PDE-5 inhibitors ... Hyperplasia #Prostate #Pathophysiology ... #Medications #Pharmacology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Decr Protease inhibitors ... Changes in collagen types ... #Keratoconus #pathophysiology
Retroviral Infections: Mechanisms of Oncogenesis
Note: A retrovirus is an RNA virus that uses reverse transcriptase to
lymphotropic virus type ... #oncogenesis #pathophysiology ... #immunology #oncology