The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... neurological findings #GiantCell ... #Pathophysiology ... #Diagnosis #Signs
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... #pathophysiology ... #msk #orthopedics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
- Arthralgia, Arthritis ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms ... #diagnosis
Reactive Arthritis
 • Inflammation of joints (commonly large joints)
    - Asymmetric Oligoarthritis: Joint
Reactive Arthritis ... Enthesitis: Commonly Achilles ... ReactiveArthritis #pathophysiology ... #diagnosis #signs
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
(PBC), or with systemic ... like rheumatoid arthritis ... (RA) or systemic ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... weight-bear • Arthritic ... FemoralHead #Fractures #msk ... #diagnosis #pathophysiology ... #signs #symptoms
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
of the Hip • Arthritis ... Trendelenburg #Gait #pathophysiology ... causes #symptoms #signs ... #diagnosis #msk
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
Rheumatoid arthritis ... deviation, etc • Systemic ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms ... #diagnosis
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
is oftentimes systemic ... in Rheumatoid arthritis ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis ... #pathophysiology
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings
 • Idiopathic
 • Meniscal Lesions
 • Osteoarthritis
 • Rheumatoid
• Rheumatoid Arthritis ... Popliteal #BakersCyst #MSK ... #pathophysiology ... #signs #symptoms ... #diagnosis