The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology vasculitis msk lupus sle disease erythematosus extraarticular giantcell orthopedics otitismedia ra rheumatoidarthritis systemic achilles anaphylaxis ankylosingspondylitis avascularnecrosis causes cholesteatoma
Giant Cell (Temporal) Arteritis: Clinical findings and Complications Signs/Symptoms: - Headache (usually constant, superimposed by waves
) Arteritis: Clinical ... Signs/Symptoms ... #Arteritis #Complications ... #Signs #Symptoms ... #diagnosis #Vasculitis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Musculoskeletal Manifestations ... - Arthralgia, Arthritis ... Musculoskeletal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Vasculitis -> Acute ... Gastrointestinal #Complications ... pathophysiology #signs ... #symptoms #diagnosis
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations Risk Factors: - Unclear environmental triggers (may be viral, not
Giant Cell (Temporal ... ) Arteritis: Pathogenesis ... yrs old; F>M Signs ... /Symptoms: - Fever ... #Diagnosis #Signs
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... weight-bear • Arthritic ... Fractures #msk #diagnosis ... pathophysiology #signs
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Acute onset of skin ... Signs / Symptoms ... / Complications ... pathophysiology #immunology #diagnosis ... #signs #symptoms
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... becomes more severe Signs ... /Symptoms/Complications ... pathophysiology #symptoms ... #signs #diagnosis
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... , Carditis #Acute ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... /Symptoms/Complications ... TendonRupture #diagnosis ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Mucocutaneous Manifestations ... Mucocutaneous #Manifestations ... pathophysiology #diagnosis ... #signs #symptoms ... #complications
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