The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... the pancreas, Vasculitis ... -> Acute Pancreatitis ... Pseudo-Obstruction: Abdominal pain ... pathophysiology #signs #symptoms
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Polyarteritis Nodosa (PAN ... swelling - GI Manifestations ... multiplex #PAN ... Diagnosis #Signs #Symptoms ... #Vasculitis
Rheumatoid arthritis (RA): Extra-articular manifestations
Skin: 
 • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... blood vessels (vasculitis ... -> Sudden eye pain ... pleuritic chest pain ... pathophysiology #signs #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... squeeze test) - Pain ... diagnosis #signs #symptoms ... pathophysiology #msk #orthopedics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Loss of pain and ... weakness and #Acute ... pathophysiology #signs #symptoms ... #msk #orthopedics
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... capsule or bone -> Pain ... Diagnosis #signs #symptoms ... #msk #orthopedics
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
poly-articular joint pain ... Extra-articular manifestations ... • Non-specific Acute-phase ... arthralgia (joint pain ... pathophysiology #signs #symptoms
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
, Incr risk of Acute ... - Abdominal Pain ... Claudication (pain ... Takayasus #Arteritis #Vasculitis ... Diagnosis #Signs #Symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... visual acuity, eye pain ... - Inflammation acute ... Extraarticular #Manifestations ... diagnosis #signs #symptoms