The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Akathisia • SSRI Withdrawal ... Syndrome - ... Serotonin #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... CubitalTunnel #Syndrome ... #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... #Pharmacology # ... Psychiatry #Diagnosis #Signs
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... weakness and #Acute ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... Patellofemoral #Syndrome ... #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... - Budd Chiari Syndrome ... Complications #pathophysiology ... #signs #symptoms
Shoulder Impingement Syndrome (SIS): Signs and Symptoms

Repetitive Overhead Activity, Scapular Dyskinesis -> Scapulohumeral mechanics become altered
Shoulder Impingement Syndrome ... (SIS): Signs and ... SIS #diagnosis #signs ... #symptoms #msk ... #pathophysiology
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Stevens-Johnson Syndrome ... decr intake -> Withdrawal ... #SideEffects #Pathophysiology ... #Psychiatry #Pharmacology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... symptoms are more acute ... The less acute behavioral ... #Opiate #Pathophysiology ... #Diagnosis #Signs
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... #CaudaEquina #Syndrome ... #MSK #pathophysiology ... diagnosis #symptoms #signs