The Calgary Guide to Understanding Disease @TheCalgaryGuide
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definitions hypersensitivity pathophysiology types anticonvulsants hypersensitivityreaction immunology mechanism moodstabilizers pharmacology psychiatry sideeffects type4 typeiv
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Stevens-Johnson Syndrome ... #Allergic #Reactions ... #Types #Classification
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... An allergic reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... development of allergen-specific ... Allergic reaction ... Initial exposure to allergen ... Stevens-Johnson Syndrome
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... reaction -> Benign ... mediated cytotoxic reaction ... Stevens-Johnson Syndrome
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