The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms complications ophthalmology orthopedics chondrocalcinosis extraarticular pseudogout ra rheumatoidarthritis achilles adhesivecapsulitis agammaglobulinemia alzheimersdisease ankylosingspondylitis anterior avascularnecrosis bakerscyst benign bph
Pseudogout: pathogenesis and clinical findings - Idiopathic (vast majority of cases) -> Mechanism unknown - Familial
vast majority of cases ... pyrophosphate dihydrate (CPPD ... and/or x-ray - CPPD ... #Disease #Signs ... Pathophysiology #Diagnosis
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... pathophysiology #signs ... #symptoms #diagnosis
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... pre-determined etiology Signs ... TendonRupture #diagnosis ... #signs #symptoms ... pathophysiology #msk
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Alzheimer’s Disease ... Alzheimer's (99% of cases ... chromosome 21) Signs ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... #Disease #Signs ... Pathophysiology #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Injury #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... lumbar spine Signs ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis ... #symptoms #signs
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
to glenoid -> Acute ... #Dislocation #Diagnosis ... #signs #symptoms ... #msk #orthopedics
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
vasoconstrictive • Acute ... hyalinization causes ... BRB breakdown causes ... ophthalmology #diagnosis ... #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... trucking" • Acute ... retinal edema caused ... ophthalmology #diagnosis ... #signs #symptoms
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