The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
below level of injury ... spinal artery injury ... below level of injury ... Syndromes #diagnosis #pathophysiology ... #orthopedics #neurology
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Periorbital Cellulitis ... considered periorbital cellulitis ... #Periorbital #Cellulitis ... #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
• Secondary glaucoma ... Retinoblastoma #pathophysiology ... #ophthalmology
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
Orbital Cellulitis ... Blindness #Orbital #Cellulitis ... #pathophysiology ... #ophthalmology
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings
OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
Acute Closed Angle Glaucoma ... present with early glaucoma ... #ClosedAngle #Glaucoma ... #pathophysiology ... #ophthalmology
Secondary Glaucoma: Pathogenesis and Clinical Findings
Open-Angle Secondary Glaucoma:
 • Pre-trabecular defect -> Aqueous outflow is obstructed
Secondary Glaucoma ... ganglion cell injury ... factors, oxidative injury ... #pathophysiology ... #ophthalmology
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
metabolites induce injury ... encephalitis and cellulitis ... peds #pediatrics #pathophysiology
Primary Open-Angle Glaucoma: Pathogenesis and Clinical Findings
 • Risk factors -> Incr IOP, Incr age, African-American
Primary Open-Angle Glaucoma ... ganglion cell injury ... factors, oxidative injury ... #pathophysiology ... #ophthalmology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Inflammation: Incr tissue injury ... chronic renal injury ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs
Cataract: Pathogenesis and clinical findings

Increased Age (most common) -> Ultraviolet light, radiation, toxins ->Denaturation and abnormal
angle closure glaucoma ... #cataracts #pathophysiology ... #ophthalmology