The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis pathophysiology signs symptoms allergic bakerscyst classification comparison cranialarteritis criteria definitions degenerative extraarticular giantcellarteritis hypersensitivity inflammatory jointdisease jointpain kawasaki polymyalgiarheumatica
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Gravis, Graves' Disease ... Erythematosus, Reactive Arthritis ... #Allergic #Reactions
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Rheumatoid arthritis ... blood vessels (vasculitis ... interstitial lung disease
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Degenerative joint disease ... Inflammatory Joint Disease ... in Rheumatoid arthritis ... Degenerative Joint Disease ... Comparison #Versus #MSK
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings - Morning Stiffness (>1
Giant Cell Arteritis ... Rheumatica and Cranial Arteritis ... Anemia of Chronic Disease ... Symptoms #Diagnosis #Vasculitis
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... : - Coronary Arteritis ... #Kawasaki #Disease ... Signs #Symptoms #Vasculitis
Popliteal (Baker’s) Cyst: Pathogenesis and clinical findings • Idiopathic • Meniscal Lesions • Osteoarthritis • Rheumatoid
• Rheumatoid Arthritis ... underlying joint disease ... underlying joint disease ... Popliteal #BakersCyst #MSK
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