The Calgary Guide to Understanding Disease @TheCalgaryGuide
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hypersensitivityreaction immunology pathophysiology classification definitions diagnosis reactions type3 type4 typei typeiv types
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... • Ex: Systemic Lupus ... Erythematosus, ... #Allergy #Allergic
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
Type I Hypersensitivity ... leading to an allergic ... cells recruited Complications ... Anaphylaxis #TypeI ... #Type1 #HypersensitivityReaction
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... : • Systemic Lupus ... • Erythematosus ... Serum sickness #TypeIII ... #Allergy #Immunology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Type IV Hypersensitivity ... mediated; exposure to allergen ... Allergic reaction ... Initial exposure to allergen ... #Allergy #Immunology
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