The Calgary Guide to Understanding Disease @TheCalgaryGuide
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allergy pathophysiology hypersensitivityreaction diagnosis classification gastrointestinal hypersensitivity signs sle symptoms systemic type1 type2 type3 type4 typei typeiii typeiv types
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
• Ex: Systemic Lupus ... Erythematosus, ... Dermatitis (ie. reaction ... #Allergic #Reactions ... Classification #Diagnosis #Definitions
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
clinical findings Definition ... leading to an allergic ... reaction. ... cells recruited Complications ... #Immunology #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
clinical findings Definition ... : • Systemic Lupus ... • Erythematosus ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
clinical findings Definition ... mediated; exposure to allergen ... Allergic reaction ... Initial exposure to allergen ... #Immunology #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Systemic Lupus Erythematosus ... the pancreas, Vasculitis ... #Systemic #Lupus ... #Erythematosus ... Gastrointestinal #Complications
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
clinical findings Definition ... antibody-mediated immune reaction ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
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